《有机化学》是研究各类有机化合物的结构、性质、相互转化及其规律的一门学科，是化学专业本科学生必修课之一，是生物化学、分子生物学、医学、药学等课程的先修课，在教学计划中占有重要的地位。 本课程主要介绍烷烃、烯烃、芳香烃、卤代烃、醇、酚、醚，醛、酮、醌、羧酸及其衍生物、胺、杂环等有机化合物的性质、相互转化以及机理问题。此外，介绍立体化学和波谱学基础。 通过本课程的学习，你能够掌握常见有机化合物的结构、命名和性质，掌握官能团之间的相互转换及其规律、以及立体化学特征、典型有机反应的机理，简单有机化合物的合成路线的设计等知识，从而为进一步的专业学习打下坚实基础。 课程结构： 本课程的学习内容包括：5~15分钟左右的视频课程，每个视频中间将出现1~2个课间提问，以辅助你的学习，每一章将会布置约10个单元练习题，课程结束后还会设立一次课程考试。 学习该课程，你需要具备高中化学知识，并具备一定的大学无机化学或普通化学基础知识。 推荐阅读： 1. 唐玉海主编，《有机化学》，化学工业出版社，2011 2. 邢其毅主编，《基础有机化学》，高等教育出版社，2009 3. John E. McMurry, Eric E. Simanek, Fundamentals of Organic Chemistry (6th), USA: 2006

The course will help train specialists in the field of processing of hydrocarbon raw materials, creating effective chemical means for protecting agricultural plants and animals, new materials, including advanced alloys (superalloys), advanced polymers, advanced composite materials, advanced ceramic materials, metal powders and metal-powder compositions, and metamaterials. The purpose of the course is to provide students with knowledge about modern technologies and methods for using composite materials with carbon fillers and their application in various industries. Composite materials with carbon fillers allow you to make innovative technical decisions and create products, helping consumers in all industries to make their production more reliable, safe, cost-effective and competitive. This course allows you to obtain the following knowledge about composite materials: - Carbon nanostructures and composite materials based on them. - Modern approaches to the creation of high-performance composite seals with carbon fillers. - Industrial technologies for producing flexible graphite foil reinforced with carbon fibers. Areas of application for flexible graphite foil. - Fireproof materials of thermally expanding type. Fire retardant materials based on intercalated graphites. Fire retardant materials based on high molecular weight ammonium polyphosphate. - Flexible composite fire retardant materials. - Thermal insulation materials on an organic and inorganic basis. - Composite materials with a changing phase state. - Thermal insulation materials for ferrous and non-ferrous metallurgy based on oxidized graphite. - The scientific basis for the creation of heat and flame retardant materials. - Key criteria for a modern approach to creating high performance seals. - Analysis of the features of the use of the most common modern materials used for the production of industrial seals. - Areas of application of materials based on polytetrafluoroethylene. - Asbestos-free composite materials based on nitrile butadiene rubbers. - High temperature sealing materials.

本课程是北京大学开设的一门在线大学化学基础课，主要面向具有大学水平的化学初学者。课程内容基本涵盖全部基础化学概念。

Please note: The capstone project is only accessible for ID-verified MicroMasters learners who successfully obtained verified certificate in all MicroMasters programme courses In this capstone project, you will focus on designing a sustainable biobased process. The emphasis of the project is on conversion. You will design a process from biomass to a finished product and discuss your choices for a catalyst, reactor type, organism and feedstock. You should be able to discuss your choices in the broad picture of sustainability while emphasising the conversion aspects of the process. The final product in this capstone project is a written report. Complete your MicroMasters credential by signing up for a virtually-proctored exam. This 2hour, multiple choice exam will test your knowledge on all topics discussed in the 3 MicroMasters programme courses. You can only start the capstone project after completingall other courses in the MicroMasters programme in Chemistry and Technology for Sustainability with a verified certificate for every course. Biorefinery: From Biomass to Building Blocks of Biobased Products ; Design an effective biorefinery to obtain valuable components from various biobased feedstocks Catalytic Conversions for Biobased Chemicals and Products ; Design new (bio)catalytic conversion routes to use biobased feedstocks to their highest potential C From Fossil Resources to Biomass: A Business and Economics Perspective ; ****Learn how to market and sell biobased products within a profitable business model

Learn about novel sensing tools that make use of nanotechnology to screen, detect and monitor various events in personal or professional life. Together, we will lay the groundwork for infinite innovative applications, starting from diagnosis and treatments of diseases, continuing with quality control of goods and environmental aspects, and ending with monitoring security issues. _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ Nanotechnology and nanosensors are broad, interdisciplinary areas that encompass (bio)chemistry, physics, biology, materials science, electrical engineering and more. The present course will provide a survey on some of the fundamental principles behind nanotechnology and nanomaterials and their vital role in novel sensing properties and applications. The course will discuss interesting interdisciplinary scientific and engineering knowledge at the nanoscale to understand fundamental physical differences at the nanosensors. By the end of the two parts of the course, students will understand the fabrication, characterization, and manipulation of nanomaterials, nanosensors, and how they can be exploited for new applications. Also, students will apply their knowledge of nanotechnology and nanosensors to a topic of personal interest in this course. - - - - - - - -- -- -- - - - - COURSE OBJECTIVES The course main objective is to enhance critical, creative, and innovative thinking. The course encourages multicultural group work, constructing international 'thinking tanks' for the creation of new ideas. Throughout the course, you will be asked to reflect upon your learning, think "out of the box", and suggest creative ideas. The two parts of the course are set to encourage the understanding of: 1. The importance of nanoscale materials for sensing applications. 2. Approaches used for characterizing sensors based nanomaterials. 3. Approaches used for tailoring nanomaterials for a specific sensing application. 4. Metallic and semiconductor nanoparticles. 5. Organic and inorganic nanotubes and nanowires. 6. Optical, mechanical and chemical sensors based on nanomaterials. 7. Hybrid nanomaterial-based sensors. ---------------- We recommend that you read the following supplementary reading materials: -Jiří Janata, Principles of Chemical Sensors, Springer, 2d Edition (1989). -Roger George Jackson, Novel Sensors and Sensing, CRC Press (2004). _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ Teaching Team About Professor Haick Hossam Professor Hossam Haick is an expert in the field of nanotechnology, nanosensors, and non-invasive disease diagnosis. Prof. Haick is the recipient of the prestigious Marie Curie Excellence Award, ERC Award, and the FP-7 Health Award. He is also the recipient of more than 42 international honors and prizes for his achievements, including a Knight of the Order of Academic Palms (conferred by the French Government) and the “List of the World’s Top 35 Young Scientists”, and the Discovery Award of the Bill & Melinda Gates. Prof. Haick is the founder and the leader of a European consortium of eight universities and companies for the development of advanced generation of nanosensors for disease diagnosis. He also serves as an associate editor of the two journals and serves as an advisory consultant to the Chemical Abstracts Service (CAS) – the world's authority for chemical information - a senior scientific advisory member of several national and international companies and institutes, and as a scientific evaluator in the European Commission. Email: [email protected] _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ Course Staff Meital Bar-Segev, Teaching Assistant: Received her B.A. (Cum Laude) in Chemistry and B.Sc (Cum Laude) in Materials Engineering from the Technion – Israel Institute of Technology (both in 2010). During her studies, she worked in a student position at Tower Semiconductors Ltd. After graduation she worked at Alfred Mann Institute in the Technion (AMIT) as a process development engineer. Currently, she performs her Ph.D. degree (direct track) in the Russell Berrie Nanotechnology Institute (RBNI) of the Technion under the supervision of Prof. Hossam Haick. The research of Meital focuses is the development of electronic skin based on nanoparticles. Abeer Watted, Teaching Assistant: Received her B.Sc. and M.Sc. in Transportation and Highways Engineering from the Technion. She is a Ph.D. student at the Faculty of Education in Science and Technology at the Technion, under the supervision of Asst. Prof. Miri Barak. She received a second master degree in Educatu in Science and Technology from the Technion in 2013. Her research focuses on science education and inquiry-based laboratories. Currently, Abeer works as a lecturer at Al-Qasemi Academic College of Education, where she serves also as the head of Civil Engineering Department. Maya Usher, Teaching Assistant: Received her B.A. and M.A. (Cum Laude) in Communication Studies from Sapir Academic College and Ben Gurion University- Israel (2009; 2013 respectively). Currently, Maya is a PhD. candidate at the Faculty of Education in Science and Technology at the Technion, under the supervision of Asst. Prof. Miri Barak. Her research focuses on examining online collaborative learning in small multicultural groups. Muhammad Khatib, Teaching Assistant: Received his B.Sc in Biochemical Engineering from the Technion – Israel Institute of Technology (2015). His final research project, conducted with Prof. Avi Schroeder, dealt with harnessing liposome-based drug delivery systems to applications in precise agriculture. Currently, he performs his Ph.D. (special track) in the Department of Chemical Engineering of the Technion under the supervision of Prof. Hossam Haick, and his research focuses on self-healing devices for monitoring infectious diseases. Miri Barak, Pedagogical Advisor: Assistant Professor at the Faculty of Education in Science and Technology, Technion- Israel Institute of Technology. She is the Head of the Science and Learning Technologies group and the advisor of graduate students. Her academic activities focus on developing, integrating, and evaluating science education curricula at school and higher education levels. Her studies involve the use of information and communication technologies (ICT), with emphasis on emerging web-2.0 and cloud applications, to foster meaningful learning and high-order thinking.

“Syntheses for Life” will start with the Bohr model of hydrogen atom and discuss chemical evolution, protein synthesis and structure, photosynthesis, and Haber’s synthesis of ammonia. The course provides an overview of remarkable scientific discoveries. First, In 1913 Bohr showed that the hydrogen line spectrum can be explained based on the nuclear model of the atom and quantum theory. Bohr model introduced the concept of energy levels for electrons in an atom and led to wave mechanics and a full understanding of chemical bonding. We will then discuss how amino acids could be produced from methane, ammonia, water and hydrogen using electric discharge as a source of energy. Chromatographic separation of simple compounds will be demonstrated. The 1953 paper in Science by Miller will be the primary source material. Third, The central dogma in protein synthesis will be briefly described. The determination of the primary structure of insulin will be discussed using Sanger’s 1958 Nobel Lecture. Experimental techniques such as electrophoresis and mass spectrometry as well as X-ray crystallography will be highlighted. We focus on the chemical principles of oxidation and reduction in photosynthesis. Calvin’s 1961 Nobel Lecture explains the role of enzymes involved in the dark reaction. How plant life and animal life are coupled by photosynthesis and respiration will be emphasized. Finally, Haber’s synthesis of ammonia is on top of the list among scientific discoveries that saved most lives. How Haber successfully selected the right process conditions and the catalyst will be described using his 1918 Nobel Lecture. Ertl’s discovery of the mechanism of the iron catalyst will also be discussed.

During each module of this course, chefs reveal the secrets behind some of their most famous culinary creations — often right in their own restaurants. Inspired by such cooking mastery, the Harvard team will then explain the science behind the recipe. Topics will include: How molecules influence flavor The role of heat in cooking Diffusion, revealed by the phenomenon of spherification, the culinary technique pioneered by Ferran Adrià. You will also have the opportunity to become an experimental scientist in your very own laboratory — your kitchen. By following along with the engaging recipe of the week, taking precise measurements, and making skillful observations, you will learn to think like both a cook and a scientist. The lab is certainly one of the most unique components of this course — after all, in what other science course can you eat your experiments?

The use of fossil resources is a controversial topic and there is much scientific research to argue against their use for energy, chemicals, and in the production of almost every product. Because of this, we're seeing a huge shift towards sustainable biobased and renewable resources and away from fossil-based ones. In this new world, it's critical to know how to efficiently and effectively obtain valuable elements from biomass. Jointhis course and gain the latest academic knowledge on biorefinery which can be applied to their ongoing studies or to advance their careers. Just as the petrochemical refinery is a crucial part of the fossil-based industry,so is the biorefinery for the biobased industry. In a biorefinery, a complex biobased feedstock is separated and processed in such a way to maximize sustainability and application opportunities. Upon completing this course, you will understand the tools and techniques needed to efficiently disentangle, separate and convert different biomass based feedstocks into simpler (functional) components. First, you'll learn about available techniques and processes for biomass activation, disentanglement and separation. Next, you'll explore how to design a biorefinery taking into account feedstock and sustainable energy use and dive into: Mass and energy balances Design of biorefinery process units to obtain multiple products from one type of biomass How to recover energy and resources in the biorefinery system Evaluation of the designed system with respect to sustainability and economic criteria Evaluation of criteria for successful implementation This course is part of the MicroMasters programme in Chemistry and Technology for Sustainability : a series of 3 courses and a final capstone project designed to help you develop the skills needed to seize opportunities and embrace the transition from a fossil-based economy to a biobased one.It'sespecially valuable to those who have (or ambition to have) a career in industries such as: (bio)chemical industry, agrifood water companies, energy producers, logistics, and related (non-)governmental organizations. Explore the other courses in the MicroMasters programme: Catalytic Conversions for Biobased Chemicals and Products From Fossil Resources to Biomass: A Business and Economics Perspective Capstone - Final project and exam (only available to learner who have obtained a verified certificate in all other courses of the MicroMasters programme).

For an entrepreneur thinking about one day starting a craft distillery, a thorough understanding of water and water chemistry is important. Water is a key raw ingredient in the craft distilling process. This course comprises 5 lectures and will help you gain a more thorough appreciation of water and its importance in craft distilling.

This course is an introduction to high-throughput experimental methods that accelerate the discovery and development of new materials. It is well recognized that the discovery of new materials is the key to solving many technological problems faced by industry and society. These problems include energy production and utilization, carbon capture, tissue engineering, and sustainable materials production, among many others. This course will introduce the learner to a remarkable new approach to materials discovery and characterization: high-throughput materials development (HTMD). Engineers and scientists working in industry, academic or government will benefit from this course by developing an understanding of how to apply one element of HTMD, high-throughput experimental methods, to real-world materials discovery and characterization problems. Internationally leading faculty experts will provide a historical perspective on HTMD, describe preparation of ‘library’ samples that cover hundreds or thousands of compositions, explain techniques for characterizing the library to determine the structure and various properties including optical, electronic, mechanical, chemical, thermal, and others. Case studies in energy, transportation, and biotechnology are provided to illustrate methodologies for metals, ceramics, polymers and composites. The Georgia Tech Institute for Materials (IMat) developed this course in order to introduce a broad audience to the essential elements of the Materials Genome Initiative. Other courses will be offered by Georgia Tech through Coursera to concentrate on integrating (i) high-throughput experimentation with (ii) modeling and simulation and (iii) materials data sciences and informatics. After completing this course, learners will be able to • Identify key events in the development of High-Throughput Materials Development (HTMD) • Communicate the benefits of HTMDwithin your organization. • Explain what is meant by high throughput methods (both computational and experimental), and their merits for materials discovery/development. • Summarize the principles and methods of high throughput creation/processing of material libraries (samples that contain 100s to 1000s of smaller samples). • State the principles and methods for high-throughput characterization of structure. • State the principles and methods for high throughput property measurements. • Identify when high-throughput screening (HTS) will be valuable to a materials discovery effort. • Select an appropriate HTS method for a property measurement of interest. • Identify companies and organizations working in this field and use this knowledge to select appropriate partners for design and implementation of HTS efforts. • Apply principles of experimental design, library synthesis and screening to solve a materials design challenge. • Conceive complete high-throughput strategies to obtain processing-structure-property (PSP) relationships for materials design and discovery.